Langerhans' Cell Histiocytosis Mimicking a Pott Puffy Tumor

J Pediatr Hematol Oncol. 2018 Apr;40(3):e182-e184. doi: 10.1097/MPH.0000000000000884.


Langherans' cell histiocytosis (LCH) is a rare disease mostly affecting children in the first decade of life. As clinical presentation is extremely heterogenous, a prompt diagnosis may be challenging, sometimes leading to a diagnostic delay, especially when the disease involves a single site. Herein, we report a case of a child with an unusual presentation of (LCH) mimicking a Pott puffy tumor with extracranial and epidural abscesses, surgically treated. Through this unique case we summarize possible manifestations of LCH with bone involvement and we underline the importance of considering possible complications due to bone erosions such as infection, to avoid a misdiagnosis.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diagnosis, Differential
  • Histiocytosis, Langerhans-Cell / diagnosis*
  • Histiocytosis, Langerhans-Cell / pathology*
  • Humans
  • Male
  • Pott Puffy Tumor / diagnosis*
  • Pott Puffy Tumor / pathology