Benefits of maggot debridement therapy on leg ulcers: a literature review

Br J Community Nurs. 2017 Jun 2;22(Sup6):S14-S19. doi: 10.12968/bjcn.2017.22.Sup6.S14.


Maggot debridement therapy (MDT) is an effective method for debriding wounds such as leg ulcers, supporting the concept of wound bed preparation ( Dumville et al, 2009 ; Soares et al, 2009 ; Mudge et al, 2014 ). New evidence is emerging to suggest that maggots might contribute to wound healing in other ways. For example, the reduction of biofilms and disinfection of wounds ( Van Der Plas et al, 2008 ; Brown et al, 2012 ; Pritchard and Brown, 2015 ) plus regulation of protease levels ( Chambers et al, 2003 ; Van Der Plas et al, 2009a ; Van Der Plas et al, 2009b ). This review will discuss research exploring new benefits of maggots in the management of individuals with chronic leg ulcers.

Keywords: MMPs; leg ulcers; maggot debridement therapy; peripheral vascular disease; reduction of infection.

Publication types

  • Review

MeSH terms

  • Animals
  • Biofilms
  • Debridement / methods*
  • Disinfection
  • Humans
  • Larva*
  • Leg Ulcer / microbiology
  • Leg Ulcer / therapy*
  • Matrix Metalloproteinases / metabolism
  • Peripheral Vascular Diseases / physiopathology
  • Skin / blood supply
  • Wound Healing*


  • Matrix Metalloproteinases