Human parvovirus arthropathy

Lancet. 1985 Feb 23;1(8426):419-21. doi: 10.1016/s0140-6736(85)91145-6.


19 of 153 patients attending an early-synovitis clinic were shown to have been recently infected by the human parvovirus (HPV). 5 other patients had evidence of some other closely preceding infection. HPV-infected patients typically presented with symmetrical peripheral polyarthropathy of sudden onset and moderate severity. Usually there was some improvement within 2 weeks, but in 17 patients symptoms persisted for more than 2 months, and in 3 for more than 4 years. Arthropathy in the absence of the facial rash that characterises HPV infection in children is a common presentation of the infection in adults.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arthritis / blood
  • Arthritis / diagnosis
  • Arthritis / etiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parvoviridae Infections / blood
  • Parvoviridae Infections / complications*
  • Parvoviridae Infections / diagnosis