Angiopoietin-2 acts as a survival factor for chronic lymphocytic leukemia B cells throughout Tie-2 receptor engagement

Hematol Oncol. 2018 Feb;36(1):372-375. doi: 10.1002/hon.2448. Epub 2017 Jun 4.
No abstract available

Publication types

  • Letter

MeSH terms

  • Angiopoietin-2 / genetics
  • Angiopoietin-2 / metabolism*
  • Cell Survival / genetics
  • Female
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics
  • Leukemia, Lymphocytic, Chronic, B-Cell / metabolism*
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology
  • Male
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism*
  • Receptor, TIE-2 / genetics
  • Receptor, TIE-2 / metabolism*
  • Signal Transduction*
  • Tumor Cells, Cultured

Substances

  • ANGPT2 protein, human
  • Angiopoietin-2
  • Neoplasm Proteins
  • Receptor, TIE-2