Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis

Tamara M Johnson; Melinda S Brown; Mohamed Rabbat; Jihad Slim

doi:10.4103/jgid.jgid_116_16

Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis

J Glob Infect Dis. 2017 Apr-Jun;9(2):76-78. doi: 10.4103/jgid.jgid_116_16.

Authors

Tamara M Johnson^{1

2}, Melinda S Brown^{1

2}, Mohamed Rabbat^{1

3}, Jihad Slim^{1

2}

Affiliations

¹ Department of Medicine, New York Medical College, School of Medicine, Valhalla, NY, USA.
² Department of Infectious Disease, St. Michael's Medical Center, Newark, NJ, USA.
³ Department of Infectious Disease, St. Joseph's Regional Medical Center, Paterson, NJ, USA.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting factor for this potentially fatal disease. Herein, we will report a case of HLH associated with anaplasmosis.

Keywords: Anaplasmosis; hemophagocytic lymphohistiocytosis; hemophagocytic syndrome.

Publication types

Case Reports