Cerebellar Granule Cells: Dense, Rich and Evolving Representations

Curr Biol. 2017 Jun 5;27(11):R415-R418. doi: 10.1016/j.cub.2017.04.009.

Abstract

For half a century it was assumed that granule cells use ultra-sparse encoding, but now in vivo calcium-imaging studies have shown that large ensembles of granule cells provide dense signals, which themselves evolve and adapt during training.

MeSH terms

  • Animals
  • Calcium / metabolism*
  • Cerebellum / cytology
  • Cerebellum / physiology*
  • Cytoplasmic Granules / physiology*
  • Models, Neurological*
  • Neural Pathways / physiology*
  • Neuroimaging / methods
  • Neurons / cytology
  • Neurons / physiology*
  • Zebrafish / physiology*

Substances

  • Calcium