Amyloidomas of the head and neck region are uncommon and generally considered a benign localized form of amyloidosis. Here, we describe "the unusual case of a young man" with a nasopharyngeal mass and osteolytic lesions caused by systemic light-chain amyloidosis treated successfully with a combined surgical and chemotherapy approach.
Keywords: Amyloidoma; nasopharyngeal tumor; osteolytic lesions; systemic light‐chain amyloidosis.