Obinutuzumab-induced serum sickness following salvage therapy for chronic lymphocytic leukemia

Clin Case Rep. 2017 Apr 24;5(6):891-893. doi: 10.1002/ccr3.969. eCollection 2017 Jun.


The incidence of serum sickness following treatment of CLL with obinutuzumab has not been fully characterized, but is likely rare. Consideration should be given to this diagnosis in appropriate circumstances so that effective corticosteroid therapy can be initiated to alleviate inflammatory symptoms and organ dysfunction in a timely manner.

Keywords: Chronic lymphocytic leukemia; monoclonal antibody; obinutuzumab; serum sickness.

Publication types

  • Case Reports