Associations between high-risk alcohol consumption and sarcopenia among postmenopausal women

Menopause. 2017 Sep;24(9):1022-1027. doi: 10.1097/GME.0000000000000879.


Objective: Sarcopenia is an age-related process, leading to cardio-metabolic diseases and disabilities. High-risk drinking is also closely related to diabetes, hypertension, and dyslipidemia, which are modifiable risk factors for sarcopenia. In the present study, we aimed to investigate the association between alcohol-drinking patterns and sarcopenia in Korean postmenopausal women.

Methods: Data from 2,373 postmenopausal women were analyzed from the 2008 to 2011 Korean National Health and Nutrition Examination Survey. We defined sarcopenia as two standard deviations below the sex-specific means of the appendicular skeletal muscle/weight (percentage) values of a young reference group. Participants were categorized into three groups according to alcohol-drinking patterns, as assessed by the Alcohol Use Disorders Identification Test questionnaire. The odds ratios and 95% confidence intervals for sarcopenia were calculated using multiple logistic regression analyses.

Results: In total, 8.2% of Korean postmenopausal women met criteria for sarcopenia. The prevalence of sarcopenia increased from low-risk to high-risk alcohol-drinking groups as follows: 7.6, 11.0, and 22.7%, respectively. Compared with the low-risk group, the odds ratio (95% confidence interval) for the high-risk group was 4.29 (1.87-9.82) after adjusting for age, body mass index, systolic blood pressure, total cholesterol, fasting blood glucose, household income, education level, daily calorie intake, current smoking and regular exercise, and household food security status CONCLUSIONS:: High-risk alcohol drinking was associated with a higher risk of sarcopenia in postmenopausal Korean women.

MeSH terms

  • Alcohol Drinking / adverse effects*
  • Alcohol Drinking / epidemiology*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Life Style
  • Middle Aged
  • Nutrition Surveys
  • Odds Ratio
  • Postmenopause*
  • Republic of Korea / epidemiology
  • Risk Factors
  • Sarcopenia / epidemiology*
  • Social Class