Association of the modified frailty index with adverse outcomes after penile prosthesis implantation

Aging Male. 2017 Jun;20(2):119-124. doi: 10.1080/13685538.2017.1292499. Epub 2017 Feb 28.

Abstract

Objectives: To investigate frailty as a predictor of surgical outcome in elderly patients undergoing penile prosthesis implantation.

Material and methods: A total of 54 elderly patients, above 60 years of age, underwent penile prosthesis implantation between 2012 and 2014. Their data were collected and retrospectively analyzed. A modified frailty index (mFI) was calculated for each patient based on 11 risk factors from the Canadian Study of Health and Aging Frailty Index. The 1-year adverse outcomes were correlated with mFI, patients' and procedure's risk factors.

Results: Mean age was 64.9 ± 5.2 years. No mortality was reported in our patients, however, one-year adverse outcomes were encountered in 43 (79.6%) patients. Among all studied variables, the 1-year adverse outcomes was not significantly association with mFI, but with preoperative glycosylated hemoglobin A1c (HbA1c) (p = 0.031) and associated Peyronie's disease (PD) (p = 0.000). HbA1c, dyslipidemia, hypertension, PD and duration of the procedure were predictive of infection complications (p < 0.05). Only PD and HbA1c sustained an independent significant impact.

Conclusions: mFI is not a predictive of post-penile prosthesis implantation adverse outcomes in elderly patients with impotence. Degree of diabetic control and association with PD was associated with the 1-year adverse outcomes and infection complications.

Keywords: Frailty; adverse outcomes; erectile dysfunction; modified frailty index; penile prosthesis implantation.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Erectile Dysfunction / surgery
  • Frailty / blood
  • Frailty / complications
  • Frailty / diagnosis*
  • Glycated Hemoglobin / analysis
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Operative Time
  • Penile Implantation / adverse effects*
  • Penile Induration / etiology
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human