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Modeling Human Brain Development


Modeling Human Brain Development

Kwanghun Chung. Sci Transl Med.


Human forebrain spheroids enable in vitro observation of region-specific neural migration and circuit formation during brain development.

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  • Assembly of functionally integrated human forebrain spheroids.
    Birey F, Andersen J, Makinson CD, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR, Paşca SP. Birey F, et al. Nature. 2017 May 4;545(7652):54-59. doi: 10.1038/nature22330. Epub 2017 Apr 26. Nature. 2017. PMID: 28445465 Free PMC article.

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