The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals

Pharmacogenomics. 2017 Jun;18(8):773-785. doi: 10.2217/pgs-2017-0027. Epub 2017 Jun 8.


Aim: The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals.

Materials & methods: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed.

Results: The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists.

Conclusion: Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.

Keywords: German university hospital; clinical decision support; pharmacogenomic.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Attitude of Health Personnel
  • Decision Support Systems, Clinical / statistics & numerical data*
  • Female
  • Hospitals, University / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Pharmacogenetics / statistics & numerical data*
  • Physicians / statistics & numerical data*
  • Surveys and Questionnaires
  • Young Adult