Etiology of Onychomycosis in Patients in Turkey

J Am Podiatr Med Assoc. 2018 May;108(3):253-256. doi: 10.7547/16-139. Epub 2017 Jun 8.

Abstract

Background: Onychomycosis is a chronic nail infection caused by dermatophytes, Candida, nondermatophyte molds, and Trichosporon. The purpose of this study was to identify the underlying pathogen in patients with onychomycosis in our region.

Methods: A retrospective analysis of 225 cases with onychomycosis, diagnosed over a 27-month period at the Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey, and confirmed with culture, was performed.

Results: Patient age ranged from 2 to 87 years (mean ± SD, 41.59 ± 17.61), and female patients were more commonly affected (120 cases, 53.3%) than male patients. Lateral and distal subungual onychomycosis was detected in 180 cases (80%). Etiologic agents were as follows: Trichophyton rubrum, 77 cases (34.2%); Trichophyton mentagrophytes, 30 cases (13.3%), Candida albicans, 28 cases (12.4%); Candida parapsilosis, 25 cases (11.1%); Acremonium species, one case (0.4%); Aspergillus species, two cases (0.9%); Fusarium species, four cases (1.3%); and Trichosporon species, three cases (1.3%).

Conclusions: The most frequent isolated etiologic agents were T rubrum for toenails and C albicans for fingernails.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Female
  • Foot Dermatoses / microbiology*
  • Humans
  • Male
  • Middle Aged
  • Onychomycosis / microbiology*
  • Retrospective Studies
  • Turkey
  • Young Adult