Neural Manifolds for the Control of Movement

Neuron. 2017 Jun 7;94(5):978-984. doi: 10.1016/j.neuron.2017.05.025.


The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural variability. These neural manifolds are spanned by specific patterns of correlated neural activity, the "neural modes." We discuss a model for neural control of movement in which the time-dependent activation of these neural modes is the generator of motor behavior. This manifold-based view of motor cortex may lead to a better understanding of how the brain controls movement.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / physiology
  • Humans
  • Models, Neurological
  • Motor Cortex / physiology*
  • Movement / physiology*
  • Neurons / physiology*