[Treatment experience with male hypogonadism patients]

Probl Endokrinol (Mosk). 1985 Mar-Apr;31(2):19-22.
[Article in Russian]


A noticeable masculinizing effect with a high level of testosterone (T) in the blood up to its level in healthy males was obtained during treatment of 10 patients with primary (hypergonadotropic) hypogonadism using sustanon-250 at a dose of 1 ml i. m. once in 3-4 weeks. However no decrease in the initially elevated levels of the follicle-stimulating and luteinizing hormones was observed. The treatment of 21 patients with hypogonadotropic hypogonadism by small doses of chorionic gonadotropin (CG) (up to 1500 Units i. m. 3 times a weeks) turned out ineffective. The use of high doses of CG (3000-4000 units i. m. 3 times a week) or CG combined with menopause gonadotropin in most patients of this group produced a short-term clinical effect with an elevated T level in the blood. Hypogonadotropic hypogonadism combined with an acute decrease in the response of the testes to CG treatment even at large doses was found in 4 patients under 6 years with cryptorchidism who had undergone surgery for descent of the testes into the scrotum.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Chorionic Gonadotropin / administration & dosage
  • Combined Modality Therapy
  • Cryptorchidism / physiopathology
  • Cryptorchidism / surgery
  • Drug Therapy, Combination
  • Follicle Stimulating Hormone / blood
  • Humans
  • Hypogonadism / blood
  • Hypogonadism / physiopathology
  • Hypogonadism / therapy*
  • Klinefelter Syndrome / blood
  • Klinefelter Syndrome / drug therapy
  • Klinefelter Syndrome / physiopathology
  • Luteinizing Hormone / blood
  • Male
  • Menotropins / administration & dosage
  • Middle Aged
  • Prolactin / blood
  • Testosterone / blood
  • Time Factors


  • Chorionic Gonadotropin
  • Testosterone
  • Menotropins
  • Prolactin
  • Luteinizing Hormone
  • Follicle Stimulating Hormone