Response to a wild poliovirus type 2 (WPV2)-shedding event following accidental exposure to WPV2, the Netherlands, April 2017

Euro Surveill. 2017 May 25;22(21):30542. doi: 10.2807/1560-7917.ES.2017.22.21.30542.

Abstract

On 3 April 2017, a wild poliovirus type 2 (WPV2) spill occurred in a Dutch vaccine manufacturing plant. Two fully vaccinated operators with risk of exposure were advised on stringent personal hygiene and were monitored for virus shedding. Poliovirus (WPV2-MEF1) was detected in the stool of one, 4 days after exposure, later also in sewage samples. The operator was isolated at home and followed up until shedding stopped 29 days after exposure. No further transmission was detected.

Keywords: GAPIII; containment; hygiene measures; poliovirus; wild poliovirus type 2 (WPV2).

MeSH terms

  • Containment of Biohazards*
  • Environmental Monitoring / methods
  • Feces / virology
  • Humans
  • Netherlands / epidemiology
  • Poliomyelitis / prevention & control*
  • Poliomyelitis / transmission
  • Poliovirus / isolation & purification
  • Poliovirus / pathogenicity*
  • Poliovirus Vaccine, Oral / administration & dosage*
  • Risk Assessment / methods*
  • Risk Management / methods*
  • Sewage
  • Virus Shedding
  • Water Microbiology

Substances

  • Poliovirus Vaccine, Oral
  • Sewage