Bone Morphogenic Protein Use in Spinal Surgery

John F Burke; Sanjay S Dhall

doi:10.1016/j.nec.2017.03.001

Bone Morphogenic Protein Use in Spinal Surgery

Neurosurg Clin N Am. 2017 Jul;28(3):331-334. doi: 10.1016/j.nec.2017.03.001.

Authors

John F Burke¹, Sanjay S Dhall²

Affiliations

¹ Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143-0112, USA.
² Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143-0112, USA. Electronic address: sanjaydhall@gmail.com.

PMID: 28600007
DOI: 10.1016/j.nec.2017.03.001

Abstract

Bone morphogenic protein (BMP) provides excellent enhancement of fusion in many spinal surgeries. BMP should be a cautionary tale about the use of industry-sponsored research, perceived conflicts of interest, and holding the field of spinal surgery to the highest academic scrutiny and ethical standards. In the case of BMP, not having a transparent base of literature as it was approved led to delays in allowing this superior technology to help patients.

Keywords: Bone morphogenic protein; Ethical standards; Fusion; Spinal surgery.

Publication types

Review

MeSH terms

Bone Morphogenetic Proteins / adverse effects*
Bone Morphogenetic Proteins / therapeutic use
Conflict of Interest
Drug Approval
Drug Industry / ethics
Humans
Neurosurgical Procedures
Research Support as Topic
Spinal Fusion / methods*

Substances

Bone Morphogenetic Proteins