Forty patients with bronchospasm of various origins were treated with an extempore combination of a bronchodilator, salbutamol, and an antihistamine agent, oxatomide. Good results were obtained in all cases treated with an improvement in respiratory function, prevention of dyspnoea attacks and a reduced intake of anti-asthma drugs. The few side-effects reported (four cases of drowsiness, one of tachycardia, and two of increased appetite), were of only a mild nature.