Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug;88(4):352-354.
doi: 10.1016/j.diagmicrobio.2017.05.009. Epub 2017 May 18.

Synergistic Activity of Ceftazidime-Avibactam and Aztreonam Against Serine and Metallo-β-Lactamase-Producing Gram-Negative Pathogens

Affiliations

Synergistic Activity of Ceftazidime-Avibactam and Aztreonam Against Serine and Metallo-β-Lactamase-Producing Gram-Negative Pathogens

Eric Wenzler et al. Diagn Microbiol Infect Dis. .

Abstract

This study assessed the in vitro synergy between ceftazidime, aztreonam, and ceftazidime-avibactam against serine and metallo-β-lactamase (MBL)-producing pathogens via the Etest MIC:MIC ratio and Agar-Etest synergy methods. The combination of aztreonam and ceftazidime-avibactam was synergistic against all Enterobacteriaceae. None of the tested combinations were consistently synergistic against IMP-producing P. aeruginosa.

Keywords: Avibactam; Aztreonam; Carbapenemase; Ceftazidime; Etest; Synergy; beta-Lactamase.

Similar articles

See all similar articles

Cited by 12 articles

See all "Cited by" articles

MeSH terms

Feedback