1 From the Research Medical Center, Kansas City, MO (S.P.M.); University of Texas Southwestern Medical Center, Dallas (D.K.M.); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto (B.Z.); Imperial Clinical Trials Unit, Imperial College London, London (N.R.P.); University of Washington, Seattle (S.S.E.); Medical University of Graz, Graz, Austria (T.R.P.); Florida Hospital Translational Research Institute for Metabolism and Diabetes and Sanford Burnham Prebys Medical Discovery Institute, Orlando (R.E.P.); Novo Nordisk, Søborg, Denmark (P.-M.H., M.L., K.B.-F., A.M., S.S., K.K.); and University of North Carolina School of Medicine, Chapel Hill (J.B.B.).