Prosthetic Valve Endocarditis caused by HACEK Organisms: a Case Reports and Systematic Review of the Literature

Ha Na Choi; Ki Ho Park; Soyoung Park; Jae Min Kim; Hyun Joon Kang; Jae Hun Park; Mi Suk Lee

doi:10.3947/ic.2017.49.4.282

Prosthetic Valve Endocarditis caused by HACEK Organisms: a Case Reports and Systematic Review of the Literature

Infect Chemother. 2017 Dec;49(4):282-285. doi: 10.3947/ic.2017.49.4.282. Epub 2017 May 26.

Authors

Ha Na Choi¹, Ki Ho Park¹, Soyoung Park¹, Jae Min Kim¹, Hyun Joon Kang¹, Jae Hun Park¹, Mi Suk Lee²

Affiliations

¹ Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea.
² Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea. mslee@khmc.or.kr.

Abstract

HACEK is a rare cause of prosthetic valve endocarditis (PVE). We describe 42-year-old male patient who presented with Aggregatibacter aphrophilus PVE and cerebral infarct. A. aphrophilus was isolated from his blood cultures as the sole pathogen, which was confirmed by subsequent 16S rRNA sequencing. He was treated with valve replacement surgery and an 8 week course of pathogen-directed antibiotic therapy and followed for 20 months without recurrence.

Keywords: Aggregatibacter aphrophilus; Endocarditis; HACEK; Heart valve prosthesis.

Publication types

Case Reports