Bacterial pathogens: A spoonful of sugar could be the medicine

Nature. 2017 Jun 22;546(7659):479-480. doi: 10.1038/nature23084. Epub 2017 Jun 14.

Abstract

Pili are filamentous bacterial structures that promote adhesion to host cells. It emerges that a small molecule that inhibits this adhesion can prevent colonization of the mouse gut by a pathogenic bacterium.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bacterial Adhesion*
  • Carbohydrates*
  • Gastrointestinal Tract
  • Humans
  • Mice

Substances

  • Carbohydrates