Epigenetic aging clocks in mice and men

Wolfgang Wagner

doi:10.1186/s13059-017-1245-8

Epigenetic aging clocks in mice and men

Genome Biol. 2017 Jun 14;18(1):107. doi: 10.1186/s13059-017-1245-8.

Author

Wolfgang Wagner^{1

2}

Affiliations

¹ Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, University Hospital of the RWTH Aachen, 52074, Aachen, Germany. wwagner@ukaachen.de.
² Institute for Biomedical Engineering - Cell Biology, University Hospital of the RWTH Aachen, 52074, Aachen, Germany. wwagner@ukaachen.de.

Abstract

Epigenetic clocks provide powerful tools to evaluate nutritional, hormonal, and genetic effects on aging. What can we learn from differences between species in how these clocks tick?Please see related Research articles: http://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1203-5 , http://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1186-2 , http://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1187-1 and http://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1185-3.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged, 80 and over
Aging / genetics*
Aging / pathology
Animals
Biological Clocks / genetics*
DNA Methylation / genetics*
Epigenesis, Genetic / genetics*
Humans
Mice