Effects of Artcure Diffusional Patch application on pain and functional status in lumbar disc herniation patients: a prospective randomized controlled study

Turk J Med Sci. 2017 Jun 12;47(3):874-882. doi: 10.3906/sag-1603-98.

Abstract

Background/aim: The aim of this study was to assess the efficacy of the Artcure Diffusional Patch, which contains a mixture of 6 herbal oils (oleum thymi, oleum limonis, oleum nigra, oleum rosmarini, oleum chamomilla, oleum lauriexpressum) and has a hypoosmolar lipid structure, in the conservative treatment of lumbar disc herniation patients and to show the advantages and/or possibility of using this as an alternative method to surgery.

Materials and methods: Of the 120 patients enrolled, 79 clinically diagnosed patients were included in the study. Clinical evaluations were performed on patients who had findings of protrusion or extrusion in their magnetic resonance results. The treatment group was treated with the Artcure Diffusional Patch while the control group received a placebo transdermal diffusional patch. The functional state of patients was measured using the Oswestry Disability Index and pain intensity was measured with a visual analog scale as primary outcomes. Secondary outcomes of the study were Lasegue's sign, the femoral stretching test, and paravertebral muscle spasm.

Results: The treatment group showed a dramatic recovery in the first month following the application in regards to Oswestry Disability Index scores and visual analog scale values. The patients treated with the Artcure Diffusional Patch showed a statistically significant difference in recovery as compared to the control group.

Conclusion: These findings suggest that the Artcure Diffusional Patch may be an alternative for the conservative treatment of lumbar disc herniation with radiculopathy.

Keywords: Artcure Diffusional Patch; Lumbar disc herniation; Oswestry Disability Index.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Analgesics* / administration & dosage
  • Analgesics* / therapeutic use
  • Disability Evaluation
  • Female
  • Humans
  • Intervertebral Disc Degeneration / physiopathology*
  • Intervertebral Disc Displacement / physiopathology*
  • Low Back Pain / drug therapy*
  • Lumbar Vertebrae / physiopathology*
  • Male
  • Middle Aged
  • Plant Preparations* / administration & dosage
  • Plant Preparations* / therapeutic use
  • Prospective Studies
  • Transdermal Patch
  • Treatment Outcome
  • Visual Analog Scale
  • Young Adult

Substances

  • Analgesics
  • Plant Preparations

Supplementary concepts

  • Intervertebral disc disease