Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update

Hepatol Int. 2017 Jul;11(4):317-370. doi: 10.1007/s12072-017-9799-9. Epub 2017 Jun 15.


There is great geographical variation in the distribution of hepatocellular carcinoma (HCC), with the majority of all cases worldwide found in the Asia-Pacific region, where HCC is one of the leading public health problems. Since the "Toward Revision of the Asian Pacific Association for the Study of the Liver (APASL) HCC Guidelines" meeting held at the 25th annual conference of the APASL in Tokyo, the newest guidelines for the treatment of HCC published by the APASL has been discussed. This latest guidelines recommend evidence-based management of HCC and are considered suitable for universal use in the Asia-Pacific region, which has a diversity of medical environments.

Keywords: APASL; Asia–Pacific; Hepatocellular carcinoma; Treatment algorithm.

Publication types

  • Review

MeSH terms

  • Asia
  • Carcinoma, Hepatocellular / epidemiology*
  • Carcinoma, Hepatocellular / therapy
  • Carcinoma, Hepatocellular / virology
  • Coinfection / epidemiology
  • Disease Management
  • Evidence-Based Medicine
  • Hepatitis B / epidemiology*
  • Hepatitis B / therapy
  • Hepatitis C / epidemiology*
  • Hepatitis C / therapy
  • Humans
  • Liver Neoplasms / epidemiology*
  • Liver Neoplasms / therapy
  • Liver Neoplasms / virology
  • Meta-Analysis as Topic
  • Practice Guidelines as Topic