Craniosynostosis - Recognition, clinical characteristics, and treatment

Bosn J Basic Med Sci. 2018 May 20;18(2):110-116. doi: 10.17305/bjbms.2017.2083.


Craniosynostosis is a developmental craniofacial anomaly, resulting in impairment of brain development and abnormally shaped skull. The main cause of craniosynostosis is premature closure of one or more cranial sutures. It usually occurs as an isolated condition, but may also be associated with other malformations as part of complex syndromes. When left untreated, craniosynostosis can cause serious complications, such as developmental delay, facial abnormality, sensory, respiratory and neurological dysfunction, anomalies affecting the eye, and psychological disturbances. Thus, early diagnosis, expert surgical techniques, postoperative care, and adequate follow-up are of vital importance in treating craniosynostosis.

Publication types

  • Review

MeSH terms

  • Brain / abnormalities*
  • Cranial Sutures
  • Craniosynostoses / classification
  • Craniosynostoses / diagnosis*
  • Craniosynostoses / genetics
  • Craniosynostoses / therapy*
  • Developmental Disabilities
  • Humans
  • Infant
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Prevalence
  • Skull / surgery