Phytochemical screening and in-vitro evaluation of pharmacological activities of peels of Musa sapientum and Carica papaya fruit

Nat Prod Res. 2018 Jun;32(11):1333-1336. doi: 10.1080/14786419.2017.1342089. Epub 2017 Jun 18.


Aqueous, absolute and 80% ethanolic extract of fruit peels of Musa sapientum and Carica papaya were investigated for their antibacterial activity, measured by disc diffusion method and antioxidant activity, measured by four different methods. Papaya and banana peels were found to contain terpenoids, tannins, alkaloids, saponins steroid, phenols, fixed oils and fats. 80% ethanolic extract of banana peel was found to contain highest total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity but in papaya peel, highest TPC and reducing activity was shown by water extract while, TFC and radical scavenging activity was given by 80% ethanolic extract. In banana, water extract showed highest antibacterial activity against tested bacteria while in case of papaya, absolute ethanolic extract showed highest antibacterial activity. The present study revealed that peels of banana and papaya fruits are potentially good source of antioxidant and antibacterial agents.

Keywords: Banana; antibacterial activity; antioxidant activity; biological waste; papaya.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Carica / chemistry*
  • Drug Evaluation, Preclinical / methods
  • Ethanol / chemistry
  • Flavonoids / analysis
  • Fruit / chemistry
  • Microbial Sensitivity Tests
  • Musa / chemistry*
  • Phenols / analysis
  • Phytochemicals / analysis
  • Plant Extracts / chemistry
  • Tannins / analysis


  • Anti-Bacterial Agents
  • Antioxidants
  • Flavonoids
  • Phenols
  • Phytochemicals
  • Plant Extracts
  • Tannins
  • Ethanol