Cell Division: Centrosomes Have Separation Anxiety

Curr Biol. 2017 Jun 19;27(12):R601-R603. doi: 10.1016/j.cub.2017.04.050.

Abstract

Prior to mitosis, duplicated centrosomes are tethered together, which is thought to prevent mitotic defects. A new study establishes the role of tetrameric Kif25, a microtubule minus-end-directed kinesin-14 motor, in preventing premature centrosome separation through a microtubule-dependent pathway.

Publication types

  • Comment

MeSH terms

  • Anxiety, Separation
  • Centrosome
  • Humans
  • Kinesin / genetics*
  • Microtubules
  • Mitosis
  • Spindle Apparatus*

Substances

  • KIF25 protein, human
  • Kinesin