Challenges in the Development of Novel Cardiovascular Therapies

Clin Pharmacol Ther. 2017 Aug;102(2):194-196. doi: 10.1002/cpt.703. Epub 2017 Jun 23.


Cardiovascular disease accounts for nearly one in three deaths globally, but few novel therapies have reached patients and clinicians in recent years. This translational report reviews trends in the development and approval of cardiovascular drugs and evaluates recent innovation in the field of cardiovascular disease therapeutics. New policies are needed to better support the development of safe and effective therapies with the greatest potential to improve patient health outcomes.

Publication types

  • Review

MeSH terms

  • Cardiovascular Agents / therapeutic use*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / drug therapy*
  • Drug Discovery / methods
  • Drug Discovery / trends*
  • Humans
  • Translational Research, Biomedical / methods
  • Translational Research, Biomedical / trends*


  • Cardiovascular Agents