Regenerating axons form nerve terminals at astrocytes

Brain Res. 1985 Nov 11;347(1):188-91. doi: 10.1016/0006-8993(85)90911-4.

Abstract

In adult rats ventral root (cholinergic axons) or hypogastric nerve (catecholaminergic axons) has been coapted to ganglionectomized dorsal root. The cholinergic and catecholaminergic fibers elongate as far as the peripheral-central nervous border. At this point some fibres were observed to have made synaptoid nerve terminals among astrocytes. The nerve endings accumulated transmitter substance even though they made no neuronal synapses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Astrocytes / ultrastructure*
  • Microscopy, Electron
  • Nerve Regeneration*
  • Neurotransmitter Agents / metabolism
  • Rats
  • Rats, Inbred Strains
  • Spinal Cord / ultrastructure*
  • Spinal Nerves / injuries*
  • Spinal Nerves / metabolism
  • Spinal Nerves / ultrastructure
  • Synapses / ultrastructure

Substances

  • Neurotransmitter Agents