Quantification of aortic valve calcification on contrast-enhanced CT of patients prior to transcatheter aortic valve implantation

Matthias Eberhard; Monika Mastalerz; Thomas Frauenfelder; Felix C Tanner; Francesco Maisano; Fabian Nietlispach; Burkhardt Seifert; Hatem Alkadhi; Thi Dan Linh Nguyen-Kim

doi:10.4244/EIJ-D-17-00060

Quantification of aortic valve calcification on contrast-enhanced CT of patients prior to transcatheter aortic valve implantation

EuroIntervention. 2017 Oct 20;13(8):921-927. doi: 10.4244/EIJ-D-17-00060.

Authors

Matthias Eberhard¹, Monika Mastalerz, Thomas Frauenfelder, Felix C Tanner, Francesco Maisano, Fabian Nietlispach, Burkhardt Seifert, Hatem Alkadhi, Thi Dan Linh Nguyen-Kim

Affiliation

¹ Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland.

PMID: 28649950
DOI: 10.4244/EIJ-D-17-00060

Abstract

Aims: The aim of the study was to develop a formula enabling the quantification of aortic valve calcification (AVC) on contrast-enhanced CT of patients undergoing transcatheter aortic valve implantation (TAVI).

Methods and results: Two hundred and seventeen (217) consecutive patients with severe aortic valve stenosis undergoing non-enhanced electrocardiography-gated CT angiography (NECT) and contrast-enhanced electrocardiography-gated CT angiography (CECT) prior to TAVI were subdivided into a training cohort (n=145) and a validation cohort (n=72). Aortic valve calcification (AVC) was semi-automatically segmented on CECT (AVC.

MeSH terms

Aged
Aged, 80 and over
Aortic Valve / pathology*
Aortic Valve / surgery
Aortic Valve Insufficiency / surgery*
Aortic Valve Stenosis / surgery*
Calcinosis / surgery*
Cardiac Catheterization / methods
Computed Tomography Angiography / methods
Female
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation* / methods
Humans
Male
Transcatheter Aortic Valve Replacement*

Supplementary concepts

Aortic Valve, Calcification of