Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.
Copyright 2017 by the National Academy of Sciences. All rights reserved.
- The National Academies of SCIENCES • ENGINEERING • MEDICINE
- COMMITTEE ON PREVENTING DEMENTIA AND COGNITIVE IMPAIRMENT
- ACRONYMS AND ABBREVIATIONS
- COMMUNICATING WITH THE PUBLIC ABOUT INTERVENTIONS TO PREVENT COGNITIVE DECLINE AND DEMENTIA
- METHODOLOGICAL IMPROVEMENTS
- PRIORITIES FOR FUTURE RESEARCH
Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force [Internet]JS Lin et al. PMID 24354019. - ReviewWe found no trial evidence that examined the effect of screening for cognitive impairment on patient, caregiver, or clinician decisionmaking or important patient, caregiv …
Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke AssociationPB Gorelick et al. Stroke 42 (9), 2672-713. PMID 21778438. - ReviewVascular contributions to cognitive impairment and dementia are important. Understanding of VCI has evolved substantially in recent years, based on preclinical, neuropath …
Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?C Hertzog et al. Psychol Sci Public Interest 9 (1), 1-65. PMID 26162004.In this monograph, we ask whether various kinds of intellectual, physical, and social activities produce cognitive enrichment effects-that is, whether they improve cognit …
Dementia and Its Implications for Public HealthDP Chapman et al. Prev Chronic Dis 3 (2), A34. PMID 16539775. - ReviewDespite the growing availability of pharmacologic and psychosocial interventions that are potentially helpful to people with dementia and their caregivers, the majority o …
Physical Activity in Community Dwelling Older People: A Systematic Review of Reviews of Interventions and ContextO Olanrewaju et al. PLoS One 11 (12), e0168614. PMID 27997604. - Clinical TrialPA can offer small benefits to brain health, but evidence on how much activity is required to produce this effect is lacking. Evidence on the effectiveness of PA for prev …
Cited by 8 PubMed Central articles
Physical Exercise and Cognitive Engagement Outcomes for Mild Neurocognitive Disorder: A Group-Randomized Pilot TrialL De Wit et al. Trials 19 (1), 573. PMID 30340619. - Randomized Controlled TrialClinicalTrials.gov, NCT03095170 . Registered on 23 March 2017.
Cognitive Impairment in Parkinson's Disease: A Report From a Multidisciplinary Symposium on Unmet Needs and Future Directions to Maintain Cognitive HealthJG Goldman et al. NPJ Parkinsons Dis 4, 19. PMID 29951580. - ReviewPeople with Parkinson's disease (PD) and their care partners frequently report cognitive decline as one of their greatest concerns. Mild cognitive impairment affects appr …
Mediterranean Diet, Its Components, and Amyloid Imaging BiomarkersM Vassilaki et al. J Alzheimers Dis 64 (1), 281-290. PMID 29889074.Findings are consistent with previous studies suggesting that higher adherence to a MeDi pattern and higher vegetable consumption are associated with better neuroimaging …
Estimation of Lifetime Risks of Alzheimer's Disease Dementia Using Biomarkers for Preclinical DiseaseR Brookmeyer et al. Alzheimers Dement 14 (8), 981-988. PMID 29802030.Lifetime risks of AD dementia vary considerably by age, gender, and the preclinical or clinical disease state of the individual. For example, the lifetime risks for a fem …
Trends in the Prevalence and Disparity in Cognitive Limitations of Americans 55-69 Years OldH Choi et al. J Gerontol B Psychol Sci Soc Sci 73 (suppl_1), S29-S37. PMID 29669102.In models controlling for age, gender, and previous cognitive testing, we find no significant change over time in the overall prevalence of CL, widening disparities in li …