Determinants of gestational diabetes mellitus: a case-control study

J Matern Fetal Neonatal Med. 2018 Oct;31(19):2584-2589. doi: 10.1080/14767058.2017.1347923. Epub 2017 Jul 9.

Abstract

Background: Gestational diabetes mellitus (GDM) is glucose intolerance first recognized during pregnancy. The objective of this study was to identify the determinant factors of GDM.

Methods: An unmatched case-control study was conducted. Descriptive statistics were used to describe the profile of study participants and binary logistic regression was used to identify the determinants of GDM.

Results: GDM was associated with history of abortion (AOR 5.05 [95% CI: 2.65-9.63]), family history of diabetes mellitus (AOR 8.63 [95% CI: 5.19-14.35]), chronic hypertension (AOR 4.63 [95% CI: 1.27-16.86]), dietary diversification score (AOR 2.96 [95% CI: 2-4.46]), regular physical exercise (AOR 0.03 [95% CI: 0.01-0.04]), history of infertility (AOR 6.19 [95%CI: 1.86-20.16]), history of Caesarean section (AOR 3.24 [95% CI: 1.58-6.63]), previous history of GDM (AOR 8.21 [95% CI: 3.18-21.24]), previous history of intrauterine fetal death (AOR 3.96 [95% CI: 1.56-10.04]), literacy (AOR 0.6 [95% CI: 0.43-0.85]), body mass index (AOR 2.96 [95% CI: 2.08-4.2]), parity (AOR 1.78 [95% CI: 1.3-2.49]).

Conclusions: Regular physical exercise should be used as the main tool in preventing GDM.

Keywords: Determinants; Ethiopia; gestational diabetes mellitus.

MeSH terms

  • Adult
  • Case-Control Studies
  • Diabetes, Gestational / epidemiology*
  • Diabetes, Gestational / prevention & control
  • Ethiopia / epidemiology
  • Exercise
  • Female
  • Humans
  • Pregnancy
  • Young Adult