Determinants of quality of life in adults with CHD: an Australian cohort

Cardiol Young. 2017 Oct;27(8):1571-1576. doi: 10.1017/S1047951117000816. Epub 2017 Jun 27.


Background: Following improved survival rates in children with CHD, their quality of life and its determinants have become increasingly important. As part of a multicentre study entitled "Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart Disease - International Study", this article reviews the relationships among quality of life, anxiety and depression, sense of coherence, and severity of disease in an Australian cohort of adults with CHD. Methods and results Adults with CHD were recruited from a single, community-based cardiology practice. All patients completed a self-reported questionnaire. A total of 135 patients, 71 males and 64 females, were recruited with a mean age of 26 years. The median quality of life in this cohort was 90; one-fifth of the patients experienced symptoms of anxiety. There was a significant negative correlation between quality of life and symptoms of anxiety and depression and a positive correlation between quality of life and sense of coherence.

Conclusions: The quality of life of this cohort was generally excellent; however, one-fifth of them experienced symptoms of anxiety. Those with less anxiety and depression symptoms appeared to have a better quality of life, as did those who reported a higher sense of coherence. Interestingly, there was no significant relationship between complexity of CHD and quality of life.

Keywords: Adult; CHD; anxiety; depression; quality of life.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Anxiety / epidemiology
  • Anxiety / etiology*
  • Anxiety / psychology
  • Depression / epidemiology
  • Depression / etiology*
  • Depression / psychology
  • Female
  • Follow-Up Studies
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / epidemiology
  • Heart Defects, Congenital / psychology*
  • Humans
  • Male
  • Middle Aged
  • Morbidity / trends
  • Prognosis
  • Quality of Life*
  • Retrospective Studies
  • Self Report*
  • Surveys and Questionnaires
  • Survival Rate / trends
  • Victoria / epidemiology
  • Young Adult