Variation in the Diagnostic Evaluation among Persons with Hematuria: Influence of Gender, Race and Risk Factors for Bladder Cancer

J Urol. 2017 Nov;198(5):1033-1038. doi: 10.1016/j.juro.2017.06.083. Epub 2017 Jun 24.

Abstract

Purpose: We sought to determine whether race, gender and number of bladder cancer risk factors are significant predictors of hematuria evaluation.

Materials and methods: We used self-reported data from SCCS (Southern Community Cohort Study) linked to Medicare claims data. Evaluation of subjects diagnosed with incident hematuria was considered complete if imaging and cystoscopy were performed within 180 days of diagnosis. Exposures of interest were race, gender and risk factors for bladder cancer.

Results: Of the 1,412 patients evaluation was complete in 261 (18%). On our adjusted analyses African American patients were less likely than Caucasian patients to undergo any aspect of evaluation, including urology referral (OR 0.72, 95% CI 0.56-0.93), cystoscopy (OR 0.67, 95% CI 0.50-0.89) and imaging (OR 0.75, 95% CI 0.59-0.95). Women were less likely than men to be referred to a urologist (OR 0.59, 95% CI 0.46-0.76). Also, although all patients with 2 or 3 risk factors had 31% higher odds of urology referral (OR 1.31, 95% CI 1.02-1.69), adjusted analyses indicated that this effect was only apparent among men.

Conclusions: Only 18% of patients with an incident hematuria diagnosis underwent complete hematuria evaluation. Gender had a substantial effect on referral to urology when controlling for socioeconomic factors but otherwise it had an unclear role on the quality of evaluation. African American patients had markedly lower rates of thorough evaluation than Caucasian patients. Number of risk factors predicted referral to urology among men but it was otherwise a poor predictor of evaluation. There is opportunity for improvement by increasing the completion of hematuria evaluations, particularly in patients at high risk and those who are vulnerable.

Keywords: African Americans; hematuria; outcome and process assessment (health care); urinary bladder neoplasm; women.

MeSH terms

  • Cystoscopy / statistics & numerical data
  • Diagnostic Imaging / statistics & numerical data
  • Healthcare Disparities / statistics & numerical data*
  • Hematuria / etiology*
  • Humans
  • Medicare / statistics & numerical data
  • Race Factors / statistics & numerical data
  • Referral and Consultation / statistics & numerical data
  • Risk Factors
  • Self Report
  • Sex Factors
  • United States / epidemiology
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / diagnostic imaging
  • Urinary Bladder Neoplasms / epidemiology*
  • Urology / statistics & numerical data