Towards a perceptive understanding of size in cellular biology

Nat Methods. 2017 Jun 29;14(7):662-665. doi: 10.1038/nmeth.4300.

Abstract

Cells are minute-typically too small to be seen by the human eye. Even so, the cellular world encompasses a range of scales, from roughly a tenth of a nanometer (10-10 m) to a millimeter (10-3 m) or larger, spanning seven orders of magnitude or more. Because they are so far from our experience, it is difficult for us to envision such scales. To help our imagination grasp such dimensions, I propose the adoption of a 'perceptive scale' that can facilitate a more direct experience of cellular sizes. From this, as I argue below, will stem a new perception also of biological shape, cellular space and dynamic processes.

MeSH terms

  • Animals
  • Cell Biology*
  • Cell Size*
  • Cytological Techniques* / instrumentation
  • Cytological Techniques* / methods
  • Humans
  • Pattern Recognition, Visual*
  • Size Perception*