Adsorption Kinetics, Isotherm, and Thermodynamics Studies of acetyl-11-keto-β-boswellic Acids (AKBA) From Boswellia Serrata Extract Using Macroporous Resin

Prep Biochem Biotechnol. 2017 Sep 14;47(8):804-812. doi: 10.1080/10826068.2017.1342263. Epub 2017 Jun 29.


An acetyl-11-keto-β-boswellic acid (AKBA) is potent anti-inflammatory agent found in Boswellia serrata oleogum resin. Adsorption characteristics of AKBA from B. serrata were studied using macroporous adsorbent resin to understand separation and adsorption mechanism of targeted molecules. Different macroporous resins were screened for adsorption and desorption of AKBA and Indion 830 was screened as it showed higher adsorption capacity. The kinetic equations were studied and results showed that the adsorption of AKBA on Indion 830 was well fitted to the pseudo first-order kinetic model. The influence of two parameters such as temperature (298, 303, and 308 K) and pH (5-8) on the adsorption process was also studied. The experimental data was further investigated using Langmuir, Freundlich, and Temkin isotherm models. It was observed that Langmuir isotherm model was found to be the best fit for AKBA adsorption by Indion 830 and highest adsorption capacity (50.34 mg/g) was obtained at temperature of 303 K. The values of thermodynamic parameters such as the change of Gibbs free energy (ΔG*), entropy (ΔS*), and enthalpy (ΔH*), indicated that the process of adsorption was spontaneous, favourable, and exothermic.

Keywords: Acetyl-11-keto-β-boswellic acids (AKBA); Boswellia serrata; adsorption; isotherm; kinetics; thermodynamics.

MeSH terms

  • Adsorption
  • Anti-Inflammatory Agents / chemistry*
  • Anti-Inflammatory Agents / isolation & purification
  • Boswellia / chemistry*
  • Ion Exchange Resins / chemistry
  • Kinetics
  • Porosity
  • Resins, Plant / chemistry
  • Thermodynamics
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification


  • Anti-Inflammatory Agents
  • Ion Exchange Resins
  • Resins, Plant
  • Triterpenes
  • acetyl-11-ketoboswellic acid