Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology
- PMID: 28666544
- DOI: 10.1016/j.tibtech.2017.06.002
Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology
Abstract
Alzheimer's disease (AD) is a type of dementia that causes major issues for patients' memory, thinking, and behavior. Despite efforts to advance AD diagnostic and therapeutic tools, AD remains incurable due to its complex and multifactorial nature and lack of effective diagnostics/therapeutics. Nanoparticles (NPs) have demonstrated the potential to overcome the challenges and limitations associated with traditional diagnostics/therapeutics. Nanotechnology is now offering new tools and insights to advance our understanding of AD and eventually may offer new hope to AD patients. Here, we review the key roles of nanotechnologies in the recent literature, in both diagnostic and therapeutic aspects of AD, and discuss how these achievements may improve patient prognosis and quality of life.
Copyright © 2017 Elsevier Ltd. All rights reserved.
Similar articles
-
Nanomedicines in the Management of Alzheimer's Disease: Current View and Future Prospects.Front Aging Neurosci. 2022 Jul 8;14:879114. doi: 10.3389/fnagi.2022.879114. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35875806 Free PMC article. Review.
-
Nanotechnology for Alzheimer Disease.Curr Alzheimer Res. 2017;14(11):1182-1189. doi: 10.2174/1567205014666170203125008. Curr Alzheimer Res. 2017. PMID: 28164767 Review.
-
Emerging nanotechnology for Alzheimer's disease: From detection to treatment.J Control Release. 2023 Aug;360:392-417. doi: 10.1016/j.jconrel.2023.07.004. Epub 2023 Jul 10. J Control Release. 2023. PMID: 37414222 Review.
-
Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues.Nanomedicine. 2011 Oct;7(5):521-40. doi: 10.1016/j.nano.2011.03.008. Epub 2011 Apr 6. Nanomedicine. 2011. PMID: 21477665 Review.
-
Advances in developing therapeutic strategies for Alzheimer's disease.Biomed Pharmacother. 2021 Jul;139:111623. doi: 10.1016/j.biopha.2021.111623. Epub 2021 Apr 26. Biomed Pharmacother. 2021. PMID: 33915504 Review.
Cited by
-
Role of lysosome in healing neurological disorders by nano-bioengineering.Front Neurosci. 2024 Jan 8;17:1331211. doi: 10.3389/fnins.2023.1331211. eCollection 2023. Front Neurosci. 2024. PMID: 38260032 Free PMC article. Review.
-
Multifunctional Nanocarriers for Alzheimer's Disease: Befriending the Barriers.Mol Neurobiol. 2023 Nov 15. doi: 10.1007/s12035-023-03730-z. Online ahead of print. Mol Neurobiol. 2023. PMID: 37966683 Review.
-
Detection of β-amyloid aggregates/plaques in 5xFAD mice by labelled native PLGA nanoparticles: implication in the diagnosis of alzheimer's disease.J Nanobiotechnology. 2023 Jul 10;21(1):216. doi: 10.1186/s12951-023-01957-5. J Nanobiotechnology. 2023. PMID: 37424018 Free PMC article.
-
Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders.Mol Diagn Ther. 2023 Jul;27(4):457-473. doi: 10.1007/s40291-023-00654-1. Epub 2023 May 22. Mol Diagn Ther. 2023. PMID: 37217723 Review.
-
Nanoparticle-Based Drug Delivery Systems: An Inspiring Therapeutic Strategy for Neurodegenerative Diseases.Polymers (Basel). 2023 May 5;15(9):2196. doi: 10.3390/polym15092196. Polymers (Basel). 2023. PMID: 37177342 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
