Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife

Andrologia. 2017 Dec;49(10). doi: 10.1111/and.12822. Epub 2017 Jul 3.


Human varicella zoster virus (VZV) is a member of the herpes virus family and affects humans only. Information about the presence of the virus in the semen samples of men affected by chickenpox is rather limited in the literature. Here, we reported a husband was affected by VZV during in vitro fertilisation treatment of his wife treated in our centre. The semen sample was checked for the presence of VZV by the PCR technique. The PCR result found no detectable viral DNA in the semen sample. The semen sample was then used for conventional IVF insemination and subsequently a healthy baby boy was born. This single case report suggests that the semen sample of men affected by chickenpox may be safe to use for assisted reproduction methods during the VZV infective period.

Keywords: human sperm; in vitro fertilisation (IVF); semen; varicella zoster virus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chickenpox / virology*
  • Fertilization in Vitro
  • Herpesvirus 3, Human / isolation & purification*
  • Humans
  • Male
  • Semen / virology*