Pentoxifylline intervention and drug action in scalping forehead flap for large temporal cutaneous defects

Pak J Pharm Sci. 2017 May;30(3(Special)):1173-1177.

Abstract

Pentoxifylline is widely used in the treatment of cerebrovascular disease, at present, there are a variety of drugs in the clinical expansion of the role of the skin flap, by improving or promoting blood circulation, to ensure the survival of the flap. We designed scalping forehead flap to reconstruct large temporal cutaneous defects. This flap is reliable and can give us excellent postoperative result. This design has several advantages and is worth to be promoted. The scalping forehead flap we designed is reliable. The posterior auricular artery and it branches provided enough blood supply to the scalp and forehead tissue of the flap. The frontal muscle also make the flap have a high survival rate. Large temporal cutaneous defects can be reconstructed by this novel scalping forehead flap we described. This technique is useful especially for patients who suffered malignant tumor and can not choose free flap.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Female
  • Forehead / surgery*
  • Graft Survival / drug effects*
  • Humans
  • Male
  • Middle Aged
  • Pentoxifylline / therapeutic use*
  • Phosphodiesterase Inhibitors / therapeutic use
  • Plastic Surgery Procedures / methods*
  • Scalp / transplantation*
  • Skin Transplantation / methods*
  • Surgical Flaps / blood supply*
  • Young Adult

Substances

  • Phosphodiesterase Inhibitors
  • Pentoxifylline