A viewpoint on considering physiological principles to study stress resistance and resilience with aging

Ageing Res Rev. 2017 Sep;38:1-5. doi: 10.1016/j.arr.2017.06.004. Epub 2017 Jul 1.


Adaptation to stress is identified as one of the seven pillars of aging research. Our viewpoint discusses the importance of the distinction between stress resistance and resilience, highlights how integration of physiological principles is critical for further understanding in vivo stress resistance and resilience, and advocates for the use of early warning signs to prevent a tipping point in stress resistance and resilience.

Keywords: Physiology; Resilience; Slowed aging; Stress resistance.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological*
  • Aging / physiology*
  • Humans
  • Resilience, Psychological
  • Stress, Physiological*