A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis

Lancet. 1986 Feb 8;1(8476):311-3. doi: 10.1016/s0140-6736(86)90838-x.


To compare antibiotic regimens for their effectiveness in preventing or treating wound sepsis, well-defined criteria for outcome are needed. A method of assessing wound healing has been devised that defines carefully the characteristics to be considered and how they are to be awarded points. Objective criteria are also included in the assessment. Points are given for the need for Additional treatment, the presence of Serous discharge, Erythema, Purulent exudate, and Separation of the deep tissues, the Isolation of bacteria, and the duration of inpatient Stay (ASEPSIS).

Publication types

  • Case Reports
  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Cardiac Surgical Procedures
  • Clinical Trials as Topic
  • Evaluation Studies as Topic
  • Glycopeptides / therapeutic use
  • Humans
  • Injections, Intravenous
  • Leg / surgery
  • Length of Stay
  • Male
  • Methods
  • Pilot Projects
  • Prospective Studies
  • Random Allocation
  • Sternum / surgery
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / microbiology
  • Surgical Wound Infection / prevention & control*
  • Teicoplanin
  • Time Factors


  • Anti-Bacterial Agents
  • Glycopeptides
  • Teicoplanin