The thyroid cancer epidemic, 2017 perspective

Curr Opin Endocrinol Diabetes Obes. 2017 Oct;24(5):332-336. doi: 10.1097/MED.0000000000000359.


Purpose of review: Thyroid cancer incidence and mortality trends have been identified as being consistent with overdiagnosis, and several recent efforts have been made to mitigate this problem.

Recent findings: Major guidelines for thyroid nodule management recommend against general biopsy of nodules less than 1 cm in size. Data supporting the safety of active surveillance of low-risk thyroid cancers is now recognized. Tumors previously labeled as encapsulated follicular variant papillary thyroid cancers are now recommended to be called noninvasive follicular thyroid neoplasm with papillary-like nuclear features.

Summary: Workup, diagnostic, and management of papillary thyroid cancer are changing rapidly to accommodate the recognition that many thyroid cancers are low risk and do not require aggressive, immediate intervention.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Carcinoma, Papillary / diagnosis
  • Carcinoma, Papillary / therapy
  • Humans
  • Medical Overuse
  • Neoplasm Invasiveness
  • Risk
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / diagnosis
  • Thyroid Neoplasms / epidemiology*
  • Thyroid Neoplasms / mortality
  • Thyroid Neoplasms / therapy
  • Thyroid Nodule / pathology