Clinical observations on the pathophysiology and treatment of anaphylactic cardiovascular collapse

Anaesth Intensive Care. 1986 Feb;14(1):17-21. doi: 10.1177/0310057X8601400105.


Observations in 205 patients with cardiovascular manifestations of anaphylactic shock confirmed the belief that adrenaline is the drug of first choice in management and that colloid solutions are preferable to crystalloid solutions in volume replacement. Arrhythmias and elevated filling pressures are more common in patients with cardiac disease but the sympathetic response appears to override the cardiac effects of histamine in healthy patients.

MeSH terms

  • Anaphylaxis / physiopathology*
  • Anaphylaxis / therapy
  • Blood Pressure
  • Epinephrine / therapeutic use
  • Hemoglobins / analysis
  • Histamine H1 Antagonists / therapeutic use
  • Humans
  • Tachycardia / etiology


  • Hemoglobins
  • Histamine H1 Antagonists
  • Epinephrine