Apple Pomace as Potential Source of Natural Active Compounds

Planta Med. 2017 Aug;83(12-13):994-1010. doi: 10.1055/s-0043-111898. Epub 2017 Jul 12.


Apple pomace is a waste product of the apple manufacturing industry that has been in the focus of life sciences as it represents a low-cost source of fruit-derived compounds. High fruit consumption is associated with beneficial health effects, and therefore, apple pomace and its constituents raise therapeutic interest. The present work reviews (i) the chemical constituents of apple pomace, (ii) optimized extraction methods of apple pomace compounds, and (iii) biological activities of apple pomace. Current evidence of apple pomace influence on digestion and metabolism, cholesterol and triglyceride homeostasis, diabetes, and sex hormones is summarized. Furthermore, studies regarding its antioxidative, anti-inflammatory, antiproliferative, antibacterial and antiviral effects are presented. The review concludes that apple pomace is an underutilized waste product of the apple industry with the potential of being processed for its nutritional and pharmaceutical value.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification
  • Anti-Infective Agents / pharmacology*
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Biological Products / chemistry*
  • Biological Products / isolation & purification
  • Biological Products / pharmacology
  • Cholesterol / metabolism
  • Digestion / drug effects
  • Fruit / chemistry*
  • Homeostasis / drug effects
  • Humans
  • Malus / chemistry*
  • Metabolism / drug effects
  • Triglycerides / metabolism


  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antioxidants
  • Biological Products
  • Triglycerides
  • Cholesterol