Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Oct 3:2:17.
doi: 10.1186/s40842-016-0035-7. eCollection 2016.

Thyroid nodule update on diagnosis and management

Shrikant Tamhane  1   2 , Hossein Gharib  1   2
Affiliations
Review

Thyroid nodule update on diagnosis and management

Shrikant Tamhane et al. Clin Diabetes Endocrinol. .

Abstract

Thyroid nodules are common. The clinical importance of thyroid nodules is related to excluding malignancy (4.0 to 6.5% of all thyroid nodules), evaluate their functional status and assess for the presence of pressure symptoms. Incidental thyroid nodules are being diagnosed with increasing frequency in the recent years with the use of newer and highly sensitive imaging techniques. The high prevalence of thyroid nodules necessitates that the clinicians use evidence-based approaches for their assessment and management. New molecular tests have been developed to help with evaluation of malignancy in thyroid nodules. This review addresses advances in thyroid nodule evaluation, and their management considering the current guidelines and supporting evidence.

Keywords: Benign; FNA; Malignant; Management; Molecular markers; Thyroid; Thyroid nodules; Ultrasonography.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Thyroid Nodule Workup Algorithm
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26(1):1–133. doi: 10.1089/thy.2015.0020. - DOI - PMC - PubMed
    1. Tunbridge WM, Evered DC, Hall R, et al. The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol (Oxf) 1977;7(6):481–493. doi: 10.1111/j.1365-2265.1977.tb01340.x. - DOI - PubMed
    1. Hegedus L. Clinical practice. The thyroid nodule. N Engl J Med. 2004;351(17):1764–1771. doi: 10.1056/NEJMcp031436. - DOI - PubMed
    1. Dean DS, Gharib H. Epidemiology of thyroid nodules. Best Pract Res Clin Endocrinol Metab. 2008;22(6):901–911. doi: 10.1016/j.beem.2008.09.019. - DOI - PubMed
    1. Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg. 2014;140(4):317–322. doi: 10.1001/jamaoto.2014.1. - DOI - PubMed

LinkOut - more resources