The effect of personal, familial, and environmental characteristics on acne vulgaris: a prospective, multicenter, case controlled study

G Ital Dermatol Venereol. 2019 Apr;154(2):177-185. doi: 10.23736/S0392-0488.17.05532-8. Epub 2017 Jul 11.


Background: There are only a few studies about epidemiological features of acne vulgaris in the literature. The aim of this study was to analyze demographic, clinical, familial and environmental characteristics of acne, the role of diet and aggravating factors and association of these factors with acne severity.

Methods: Patients with a diagnosis of mild-moderate to severe acne were consecutively interviewed at the participating centers during the study period.

Results: A total of 3826 patients and 759 control patients were involved in this study. Mild acne was the most common type of acne, and most of the lesions were localized on face followed by the trunk. The severity of acne was worse in patients who had a positive family history of acne. The most common triggering factor was psychological stress. We found a positive correlation with chocolate, bread, green tea, milk, white sugar, ripe banana, ice cream, apple, orange, and red meat consumption. As we compare the acne severity according to geographical features we detected mild- moderate acne was more common in Mediterranean region and severe acne was more common in East Anatolian region. Family history positivity was more common in Aegean region and least common in Central Anatolian region. There was statistically significant relationship as we compare acne severity and dietary factors such as chocolate, dairy products such as milk, sunflower seed consumption within the geographical regions.

Conclusions: This study presents the demographic and clinical characteristics of acne patients in Asian and the European parts of Turkey. We believe that this study will provide a useful overview of acne in Turkey.

Publication types

  • Multicenter Study

MeSH terms

  • Acne Vulgaris / epidemiology*
  • Acne Vulgaris / etiology
  • Acne Vulgaris / pathology
  • Adolescent
  • Adult
  • Case-Control Studies
  • Child
  • Diet / adverse effects*
  • Environment
  • Family Health*
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Stress, Psychological / complications*
  • Stress, Psychological / epidemiology
  • Turkey
  • Young Adult