Miscellaneous and Emerging Applications of Dual-Energy Computed Tomography for the Evaluation of Intracranial Pathology

Neuroimaging Clin N Am. 2017 Aug;27(3):411-427. doi: 10.1016/j.nic.2017.03.005. Epub 2017 Jun 4.


Dual-energy computed tomography (CT) has the potential to improve detection of abnormalities and increase diagnostic confidence in the evaluation of a variety of neurologic conditions by using different x-ray energy-dependent absorption behaviors of different materials. This article reviews the virtual monochromatic imaging applications of dual-energy CT, particularly material decomposition algorithms to improve lesion conspicuity, define lesion-normal tissue interface using different reconstruction techniques, and discuss miscellaneous emerging applications of dual-energy CT for neuroimaging, with an emphasis on their potential clinical utility.

Keywords: Basis material analysis; Bone removal; Bone subtraction image; Dual-energy CT; Effective atomic number; Iodine distribution map; Virtual monochromatic image.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Humans
  • Neuroimaging / methods*
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiography, Dual-Energy Scanned Projection / methods*
  • Tomography, X-Ray Computed / methods*