Studying risk factors for skin cancer development

Wiad Lek. 2017;70(3 pt 1):503-507.


Introduction: In most countries with a population of mainly European origin, non-melanoma skin carcinoma incidence rate has increased over the last decade. Understanding of what is the best way to identify people at high risk for skin cancer development will help to optimize the strategy for prevention and treatment tactics. Aim of the research involves studying risk factors for skin cancer development in patients with cutaneous squamous cell carcinoma and squamous cell carcinoma in situ (cSCC and SCCis correspondingly) and patients with actinic keratosis (AK).

Materials and methods: we conducted a survey of patients with cSCC, SCCis and AK who had been under case follow-up at the State Scientific Institution "Scientific and Practical Centre of Preventive and Clinical Medicine" of the State Administration (hereinafter SIS) during 2014-2016.Clinical diagnosis in 100% of cases was confirmed by pathomorphological study. Statistical processing of the obtained data was performed using STATISTICA 7.0 programme.

Results: The questionnaire involved 129 patients, including 21(16.3%) patient with cSCC, 40 (31%) patients with SCCis, 57 (44.2%) patients with AK and 11 (8.5%) patients who had mentioned above combined pathology i.e. cSCC, SCCis and АК at the same time. Only two studied risk factors for skin cancer development were found to have influence on the skin pathology: "Not using sun-protection preparation for the skin" and "Burdened family history of thefirst level of relationship".

Conclusions: In forming the risk groups for skin cancer development it is advisable to consider burdened family history and using sun-protection preparation for the skin.

Keywords: actinic keratosis; cutaneous squamous cell carcinoma; risk factors; squamous cell carcinoma in situ.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / etiology*
  • Female
  • Humans
  • Keratosis, Actinic*
  • Male
  • Medical History Taking
  • Middle Aged
  • Risk Factors
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / etiology*
  • Sunscreening Agents


  • Sunscreening Agents