The path to the genetic code

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2674-2679. doi: 10.1016/j.bbagen.2017.07.009. Epub 2017 Jul 14.


In December of 1966 the last nucleotide triplet in the genetic code has been assigned (Brenner et al., 1967 [1]) thus completing years of studies aimed at deciphering the nature of the relationship between the sequences of genes and proteins. The end product, the table of the genetic code, was a crowning achievement of the quest to unravel the basic mechanisms underlying functioning of all living organisms on the molecular level.

Keywords: Genetic code; Genetic information; Protein synthesis; Tie club.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence / genetics
  • Genetic Code / genetics*
  • Genetics / history*
  • History, 20th Century
  • Humans
  • Proteins / genetics*


  • Proteins